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INN Regeneration — Bioactive Complex for Restoration and Protection of the Skin Barrier
Type V Collagen, Elastin
An innovative cosmetic active based on undenatured marine Type V collagen and elastin. Helps normalize the skin’s moisture balance, improve firmness and elasticity, and smooth microrelief.
Forms a breathable protective film on the skin surface, promoting restoration of the integrity of the stratum corneum and reducing transepidermal water loss. Helps improve the overall appearance of the skin, smooth texture, and enhance tone.

INCI: AQUA, LACTIC ACID, SOLUBLE COLLAGEN (COLLAGEN PLACENTAL MARINE), ELASTIN
Recommended usage level: 1–5%
INN Regeneration Liquid PRO
Colloidal solution (pH 5.5–7.0).

5000 ml
INN Regeneration
Powder (bulk density on request)

1000 g
INN Regeneration Farm Pro
Powder (bulk density on request)

500 g
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Mechanism of Action
Native Type V collagen retains its triple-helix structure and natural amino acid sequence, ensuring high biocompatibility upon contact with the skin (98%, confirmed by testing). Due to its high molecular weight (280–300 kDa), it forms a structured biocompatible film on the skin surface that provides the following effects
  • Barrier protection
    Reduces transepidermal water loss (up to -34.7% according to clinical data), supporting restoration and maintenance of the skin barrier function
  • Hydration
    Helps maintain optimal hydration levels in the superficial layers of the skin (up to +158% according to clinical data)
  • Elasticity and tone
    Improves skin firmness and elasticity (up to +98% according to clinical data), enhances tone, and smooths microrelief
  • Texture refinement
    Improves skin texture and reduces visible irregularities
Recommended Product Categories
  • Intensive Care
    • Concentrated serums and ampoule treatments
    • Intensive night creams and masks
    • Eye contour products
    • Neck and décolleté cream concentrates
  • Restoration and Protection
    • Post-procedure products (peels, laser, injections)
    • After-sun products
    • Products for reactive and damaged skin
    • Protective and restorative balms
  • Professional Cosmetics
    • Products for salon treatment protocols
    • Professional masks
    • Pre- and post-procedure products
  • Product Lines
    • Premium anti-age (40+, 50+)
    • Dermocosmetics / pharmacy skincare
    • Professional salon lines
    • Cosmeceutical brands
Excerpt from Clinical Study
(INN Regeneration Liquid)
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Skin Hydration
Skin hydration levels increased by 148.5%, 158.3%, and 153.7% at weeks 2, 4, and 8, respectively, compared to baseline
Skin Elasticity
Elasticity improved by 89.3%, 98.1%, and 96.5% at weeks 2, 4, and 8, respectively, compared to baseline.
Transepidermal Water Loss (TEWL)
Average reduction in transepidermal water loss was 34.7% for IINN Regeneration
11.35% for placebo
Physicochemical Characteristics
  • Color: 0.1% aqueous solution is colorless; shades from light beige to gray are acceptable
  • Appearance: viscous homogeneous liquid or gel-like mass, with minor suspended particles or sediment allowed
  • Odor: characteristic odor permitted; vanilla note also acceptable (4-hydroxy-3-methoxybenzaldehyde used as a processing agent)